934-05-4
- Product Name：4-Bromo-2-(methoxycarbonyl)-1H-pyrrole
- Molecular Formula：C6H6BrNO2
- Purity：99%
- Molecular Weight：204.023
Product Details
pd_meltingpoint:100-101°C
Factory supply 4-Bromo-2-(methoxycarbonyl)-1H-pyrrole 934-05-4 with sufficient stock and high standard
- Molecular Formula:C6H6BrNO2
- Molecular Weight:204.023
- Vapor Pressure:0.002mmHg at 25°C
- Melting Point:100-101°C
- Refractive Index:1.573
- Boiling Point:290.5 °C at 760 mmHg
- PKA:13.49±0.50(Predicted)
- Flash Point:129.5 °C
- PSA：42.09000
- Density:1.674 g/cm3
- LogP:1.56380
Methyl 4-bromopyrrole-2-carboxylate(Cas 934-05-4) Usage
InChI:InChI=1/C6H6BrNO2/c1-10-6(9)5-2-4(7)3-8-5/h2-3,8H,1H3
934-05-4 Relevant articles
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Linda,Marino
, p. 499 (1967)
-
Substrate Controlled Regioselective Bromination of Acylated Pyrroles Using Tetrabutylammonium Tribromide (TBABr3)
Gao, Shuang,Bethel, Travis K.,Kakeshpour, Tayeb,Hubbell, Grace E.,Jackson, James E.,Tepe, Jetze J.
, p. 9250 - 9255 (2018/07/15)
Electrophilic bromination of pyrroles be...
Non-basic azolotriazinone MCHR1 antagonists for the treatment of obesity: An empirical brain-exposures-driven candidate selection for in vivo efficacy studies
Devasthale, Pratik,Wang, Wei,Mignone, James,Renduchintala, Kishore,Radhakrishnan, Sridhar,Dhanapal, Jayanthi,Selvaraj, Jagannath,Kuppusamy, Rajesh,Pelleymounter, Mary Ann,Longhi, Daniel,Huang, Ning,Flynn, Neil,Azzara, Anthony V.,Rohrbach, Kenneth,Devenny, James,Rooney, Suzanne,Thomas, Michael,Glick, Susan,Godonis, Helen,Harvey, Susan,Cullen, Mary Jane,Zhang, Hongwei,Caporuscio, Christian,Stetsko, Paul,Grubb, Mary,Huang, Christine,Zhang, Lisa,Freeden, Chris,Murphy, Brian J.,Robl, Jeffrey A.,Washburn, William N.
, p. 4412 - 4418 (2015/10/12)
Non-basic azolotriazinones were explored...
Vanadate-dependent bromoperoxidases from Ascophyllum nodosum in the synthesis of brominated phenols and pyrroles
Wischang, Diana,Radlow, Madlen,Hartung, Jens
, p. 11926 - 11940 (2013/09/02)
Bromoperoxidases from the brown alga Asc...
Synthesis and biological evaluation of novel substituted pyrrolo[1,2-a] quinoxaline derivatives as inhibitors of the human protein kinase CK2
Guillon, Jean,Le Borgne, Marc,Rimbault, Charlotte,Moreau, Stéphane,Savrimoutou, Solène,Pinaud, No?l,Baratin, Sophie,Marchivie, Mathieu,Roche, Séverine,Bollacke, Andre,Pecci, Adali,Alvarez, Lautaro,Desplat, Vanessa,Jose, Joachim
, p. 205 - 222 (2013/10/01)
Herein we describe the synthesis and pro...
934-05-4 Process route
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1193-62-0
methyl Pyrrole-2-carboxylate
-
-
1198-67-0
methyl 3,4,5-tribromo-1H-pyrrole-2-carboxylate
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-
934-05-4
methyl 4-bromo-1H-pyrrole-2-carboxylate
-
-
937-16-6
4,5-dibromopyrrole-2-carboxylic acid methyl ester
| Conditions | Yield |
|---|---|
|
With
bromine;
In
water; tert-butyl alcohol;
at 25 ℃;
regioselective reaction;
|
-
-
35302-72-8
pyrrol-2-yl trichloromethyl ketone
-
-
1198-67-0
methyl 3,4,5-tribromo-1H-pyrrole-2-carboxylate
-
-
934-05-4
methyl 4-bromo-1H-pyrrole-2-carboxylate
-
-
937-16-6
4,5-dibromopyrrole-2-carboxylic acid methyl ester
| Conditions | Yield |
|---|---|
|
Multi-step reaction with 2 steps
1: methanol / 0.67 h / 23 °C / Inert atmosphere
2: bromine / water; tert-butyl alcohol / 25 °C
With
methanol; bromine;
In
water; tert-butyl alcohol;
|
934-05-4 Upstream products
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67-56-1
methanol
-
72652-32-5
1-(4-bromo-1H-pyrrol-2-yl)-2,2,2-trichloroethanone
-
110-86-1
pyridine
-
192197-56-1
4-bromo-1H-pyrrole-2-carboxylic acid chloride
934-05-4 Downstream products
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86288-94-0
4-Bromo-1-((E)-styryl)-1H-pyrrole-2-carboxylic acid
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157425-54-2
5-acetyl-4-bromo-1H-pyrrole-2-carboxylic acid methyl ester
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156237-78-4
4-bromopyrrole-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester
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86288-56-4
4-Bromo-1-phenethyl-1H-pyrrole-2-carboxylic acid methyl ester
Relevant Products
-
benzyl (2-bromoethyl)carbamateCAS：53844-02-3
-
N-BOC-4-HydroxypiperidineCAS：109384-19-2
-
(R)-5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indoleCAS：143322-57-0
