109384-19-2
- Product Name：N-BOC-4-Hydroxypiperidine
- Molecular Formula：C10H19NO3
- Purity：99%
- Molecular Weight：201.266
Product Details
pd_meltingpoint:60-65 ºC
Appearance:white or off-white crystalline powder
China cas 109384-19-2 manufacturer wholesale N-BOC-4-Hydroxypiperidine at affordable price
- Molecular Formula:C10H19NO3
- Molecular Weight:201.266
- Appearance/Colour:white or off-white crystalline powder
- Vapor Pressure:0.000198mmHg at 25°C
- Melting Point:60-65 ºC
- Refractive Index:1.495
- Boiling Point:292.3 ºC at 760 mmHg
- PKA:14.80±0.20(Predicted)
- Flash Point:130.6 ºC
- PSA：49.77000
- Density:1.107 g/cm3
- LogP:1.31610
N-BOC-4-Hydroxypiperidine(Cas 109384-19-2) Usage
InChI:InChI=1/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-8(12)5-7-11/h8,12H,4-7H2,1-3H3
109384-19-2 Relevant articles
Synthesis of C-substituted cyclic amines using azacycloalkyl organozinc reagents
Billotte
, p. 379 - 380 (1998)
Azetidine and piperidine derived organoz...
One-pot synthesis of novel tert-butyl-4-substituted phenyl-1H-1,2,3-triazolo piperazine/piperidine carboxylates, potential GPR119 agonists
Bashetti, Nagaraju,Shanmukha Kumar,Seelam, Naresh Varma,Prasanna,Mintz, Akiva,Damuka, Naresh,Devanathan, Sriram,Solingapuram Sai, Kiran Kumar
, (2019)
We have synthesized a new series of 1,2,...
Design, synthesis, and biological evaluation of radioiodinated benzo[d]imidazole-quinoline derivatives for platelet-derived growth factor receptor β (PDGFRβ) imaging
Effendi, Nurmaya,Mishiro, Kenji,Takarada, Takeshi,Yamada, Daisuke,Nishii, Ryuichi,Shiba, Kazuhiro,Kinuya, Seigo,Odani, Akira,Ogawa, Kazuma
, p. 383 - 393 (2019)
Several malignant tumors and fibrotic di...
Regioselective samarium diiodide induced couplings of carbonyl compounds with 1,3-diphenylallene and alkoxyallenes: A new route to 4-hydroxy-1-enol ethers
Hoelemann, Alexandra,Reissig, Hans-Ulrich
, p. 5493 - 5506 (2004)
Since its introduction into synthetic or...
Hierarchically assembled helicates as reaction platform – from stoichiometric Diels–Alder reactions to enamine catalysis
Albrecht, Markus,Begall, Jenny,Craen, David Van,Gro?kurth, Johannes,Himmel, Leonard,Isaak, Elisabeth,Linnenberg, Oliver
, p. 2338 - 2345 (2020)
The stereoselectivity of a Diels–Alder r...
A novel amalgamation of 1,2,3-triazoles, piperidines and thieno pyridine rings and evaluation of their antifungal activity
Darandale, Sunil N.,Mulla, Nayeem A.,Pansare, Dattatraya N.,Sangshetti, Jaiprakash N.,Shinde, Devanand B.
, p. 527 - 532 (2013)
It is the first report of the novel amal...
Selective reduction of ketones using water as a hydrogen source under high hydrostatic pressure
Tomin, Anna,Lazarev, Alexander,Bere, Matthew P.,Redjeb, Hana,T?r?k, Béla
, p. 7321 - 7326 (2012)
A selective reduction of a broad variety...
An Efficient approach to the securinega alkaloids empowered by cooperative n-heterocyclic carbene/lewis acid catalysis
Elsohly, Adel M.,Wespe, Daniel A.,Poore, Tyler J.,Snyder, Scott A.
, p. 5789 - 5794 (2013)
Folding it all together: Most of the syn...
Water-soluble pleuromutilin derivative with excellent in vitro and in vivo antibacterial activity against Gram-positive pathogens
Hirokawa, Yoshimi,Kinoshita, Hironori,Tanaka, Tomoyuki,Nakata, Katsuhisa,Kitadai, Noriyuki,Fujimoto, Koichi,Kashimoto, Shigeki,Kojima, Tsuyoshi,Kato, Shiro
, p. 1991 - 1994 (2008)
Although earlier pleuromutilin analogues...
An air and moisture tolerant iminotrihydroquinoline-ruthenium(ii) catalyst for the transfer hydrogenation of ketones
Li, Jiaoyan,Ma, Yingmiao,Wang, Zheng,Liu, Qingbin,Solan, Gregory A.,Ma, Yanping,Sun, Wen-Hua
, p. 8738 - 8745 (2018)
Reaction of 8-amino-5,6,7,8-tetrahydroqu...
The first radiosynthesis of [11C]AZD8931 as a new potential PET agent for imaging of EGFR, HER2 and HER3 signaling
Wang, Min,Gao, Mingzhang,Zheng, Qi-Huang
, p. 4455 - 4459 (2014)
The reference standard AZD8931{2-(4-((4-...
N-[18F]fluoroethyl-4-piperidyl acetate ([18F]FEtP4A): A PET tracer for imaging brain acetylcholinesterase in vivo.
Zhang, Ming-Rong,Furutsuka, Kenji,Maeda, Jun,Kikuchi, Tatsuya,Kida, Takayo,Okauchi, Takashi,Irie, Toshiaki,Suzuki, Kazutoshi
, p. 2519 - 2527 (2003)
N-[(18)F]Fluoroethyl-4-piperidyl acetate...
Design of a "two-in-One" Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites
Bauer, Nicolas,Berger, Benedict-Tilman,Berger, Lena M.,Beyett, Tyler S.,Corona, Cesear R.,Eck, Michael J.,Heppner, David E.,Knapp, Stefan,Laufer, Stefan A.,Rana, Jaimin K.,Robers, Matthew B.,Schmoker, Anna M.,Shin, Bo Hee,To, Ciric,Vasta, James D.,Wittlinger, Florian,Günther, Marcel,J?nne, Pasi A.
supporting information, (2021/11/13)
Inhibitors targeting the epidermal growt...
Design, synthesis and biological evaluation of 2-substituted-6-[(4-substituted-1-piperidyl)methyl]-1H-benzimidazoles as inhibitors of ebola virus infection
Bessières, Maxime,Plebanek, El?bieta,Chatterjee, Payel,Shrivastava-Ranjan, Punya,Flint, Mike,Spiropoulou, Christina F.,Warszycki, Dawid,Bojarski, Andrzej J.,Roy, Vincent,Agrofoglio, Luigi A.
, (2021/02/06)
Novel 2-substituted-6-[(4-substituted-1-...
Sustainable Route Toward N-Boc Amines: AuCl3/CuI-Catalyzed N-tert-butyloxycarbonylation of Amines at Room Temperature
Cao, Yanwei,He, Lin,Huang, Yang
, (2021/12/22)
N-tert-butoxycarbonyl (N-Boc) amines are...
109384-19-2 Process route
-
-
118811-07-7
tert-butyl 4-(tosyloxy)piperidin-1-carboxylate
-
-
245507-96-4
C9H15ClMg
-
-
C19H33NO2
-
-
85838-94-4
N-Boc-1,2,3,6-tetrahydropyridine
-
-
109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate
| Conditions | Yield |
|---|---|
|
With
dilithium tetrachlorocuprate;
In
tetrahydrofuran;
at 40 ℃;
|
-
-
141699-59-4
1-(tert-butoxycarbonyl)piperidin-4-yl methanesulfonate
-
-
245507-96-4
C9H15ClMg
-
-
C19H33NO2
-
-
85838-94-4
N-Boc-1,2,3,6-tetrahydropyridine
-
-
109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate
| Conditions | Yield |
|---|---|
|
With
copper dichloride;
In
tetrahydrofuran;
at 20 ℃;
|
109384-19-2 Upstream products
-
5382-16-1
4-HYDROXYPIPERIDINE
-
24424-99-5
di-tert-butyl dicarbonate
-
79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one
-
75844-69-8
t-butyl piperidinecarboxylate
109384-19-2 Downstream products
-
79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one
-
162045-36-5
4-(N-t-Butoxycarbonyl-4-piperidinyloxy)-2-hydroxybenzoic acid methyl ester
-
118811-07-7
tert-butyl 4-(tosyloxy)piperidin-1-carboxylate
-
182875-01-0
4-(4-Cyano-3-fluoro-phenoxy)-piperidine-1-carboxylic acid tert-butyl ester
Relevant Products
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1-Boc-3-PiperidinoneCAS：98977-36-7
-
2-(1,2-Benzisoxazol-3-yl)acetic acidCAS：4865-84-3
-
4-Bromo-2-(methoxycarbonyl)-1H-pyrroleCAS：934-05-4
