1916-07-0
- Product Name：3,4,5-Trimethoxybenzoic acid methyl ester
- Molecular Formula：C11H14O5
- Purity：99%
- Molecular Weight：226.229
Product Details
pd_meltingpoint:81-85 °C
Appearance:white to light yellow powder
Chinese factory supply 3,4,5-Trimethoxybenzoic acid methyl ester 1916-07-0 in stock with high standard
- Molecular Formula:C11H14O5
- Molecular Weight:226.229
- Appearance/Colour:white to light yellow powder
- Vapor Pressure:0.00538mmHg at 25°C
- Melting Point:81-85 °C
- Refractive Index:1.494
- Boiling Point:274.5 °C at 760 mmHg
- Flash Point:115.2 °C
- PSA：53.99000
- Density:1.134 g/cm3
- LogP:1.49900
Methyl 3,4,5-trimethoxybenzoate(Cas 1916-07-0) Usage
InChI:InChI=1/C11H14O5/c1-13-8-5-7(11(12)16-4)6-9(14-2)10(8)15-3/h5-6H,1-4H3
1916-07-0 Relevant articles
A new cytotoxic cholestane bisdesmoside from Ornithogalum saundersiae bulbs
Mimaki, Yoshihiro,Kuroda, Minpei,Kameyama, Aiko,Sashida, Yutaka,Hirano, Toshihiko,Oka, Kitaro,Koike, Kazuo,Nikaido, Tamotsu
, p. 1049 - 1050 (1996)
Bioassay-guided fractionation of the MeO...
Phyllanemblinins A-F, new ellagitannins from Phyllanthus emblica
Zhang, Ying-Jun,Abe, Tomomi,Tanaka, Takashi,Yang, Chong-Ren,Kouno, Isao
, p. 1527 - 1532 (2001)
Six new ellagitannins, phyllanemblinins ...
Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site
Lai, Qinhuai,Wang, Yuxi,Wang, Ruixue,Lai, Weirong,Tang, Liangze,Tao, Yiran,Liu, Yu,Zhang, Ruirui,Huang, Luyi,Xiang, Haotian,Zeng, Shaoxue,Gou, Lantu,Chen, Hao,Yao, Yuqin,Yang, Jinliang
, p. 162 - 179 (2018)
Tubulin inhibitors that target the colch...
PUNICAFOLIN, AN ELLAGITANNIN FROM THE LEAVES OF PUNICA GRANATUM
Tanaka, Takashi,Nonaka, Gen-Ichiro,Nishioka, Itsuo
, p. 2075 - 2078 (1985)
A new ellagitannin, punicafolin has been...
Biologically active bergenin derivatives from bergenia stracheyi
Siddiq, Farah,Fatima, Itrat,Malik, Abdul,Afza, Nighat,Iqbal, Lubna,Lateef, Mehreen,Hameed, Saira,Khan, Sher Wali
, p. 91 - 98 (2012)
New bergenin derivatives, bergecins A an...
Synthesis of 2,3-dimethoxy-5-methyl-1,4-benzoquinone: A key fragment in coenzyme-q series
Chida,Vani,Chandrasekharam,Srinivasan,Singh
, p. 657 - 660 (2001)
Preparation of the title compound by a r...
Proton-catalyzed methanolysis and stereoelectronically controlled C-3 epimerization of reserpine
Schiffl,Pindur
, p. 443 - 450 (1986)
-
-
Jurd
, p. 3445,3446 (1956)
-
-
Bauer,Starcke
, p. 167,169 (1934)
-
Structure and biogenesis of jolkinin, a highly oxygenated ellagitannin from Euphorbia jolkinii
Lee, Seung-Ho,Tanaka, Takashi,Nonaka, Gen-Ichiro,Nishioka, Itsuo
, p. 1018 - 1022 (2004)
A new ellagitannin, jolkinin (2), was is...
Three novel C-glycosidic ellagitannins, Rhoipteleanins H, I, and J, from Rhoiptelea chiliantha
Jiang, Zhi-Hong,Tanaka, Takashi,Kouno, Isao
, p. 425 - 429 (1999)
Three novel C-glycosidic ellagitannins n...
Design and synthesis of novel parabanic acid derivatives as anticonvulsants
Aboutabl, Mona Elsayed,Hassan, Rasha Mohamed,El-Azzouny, Aida Abdel-Sattar,Aboul-Enein, Mohamed Nabil,Abd-Allah, Walaa Hamada
, (2019)
In this work a set of novel derivatives ...
Polyhydroxybenzoic acid derivatives as potential new antimalarial agents
Degotte, Gilles,Francotte, Pierre,Pirotte, Bernard,Frédérich, Michel
, (2021/08/07)
With more than 200 million cases and 400...
Synthesis, characterization (theoretical and biological study) of some transition metal complexes with new schiff base derived from 1,2,4-triazole
AL-Jibouri, Mahmoud Najim,Jawad, Waleed A.,Balakit, Asim A.,Obies, Mohammed
, p. 5229 - 5241 (2021/08/31)
The present work involves, new Schiff ba...
Antibacterial and Antiviral Activities of 1,3,4-Oxadiazole Thioether 4H-Chromen-4-one Derivatives
Cao, Xiao,Liu, Fang,Liu, Liwei,Liu, Tingting,Peng, Feng,Wang, Qifan,Xie, Chengwei,Xue, Wei,Yang, Jinsong
, p. 11085 - 11094 (2021/10/01)
Various 1,3,4-oxadiazole thioether 4H-ch...
Fluorinated benzylidene indanone exhibits antiproliferative activity through modulation of microtubule dynamics and antiangiogenic activity
Chanda, Debabrata,Fatima, Eram,Fatima, Kaneez,Khan, Feroz,Luqman, Suaib,Negi, Arvind S.,Shanker, Karuna,Shukla, Aparna,Singh, Aastha,Singh, Arjun,Srivastava, Ankita
, (2020/08/24)
The application of fluorine in drug desi...
1916-07-0 Process route
-
-
99-50-3
3,4-Dihydroxybenzoic acid
-
-
89-86-1
4-hydroxysalicylic acid
-
-
149-91-7
3,4,5-trihydroxybenzoic acid
-
-
99-10-5
3,5-Dihydroxybenzoic acid
-
-
303-38-8
2,3-Dihydroxybenzoic acid
-
-
490-79-9
2,5-dihydroxybenzoic acid.
-
-
99-06-9
3-Carboxyphenol
-
-
69-72-7,25496-36-0,8052-31-1
salicylic acid
-
-
74-88-4
methyl iodide
-
-
99-96-7
4-hydroxy-benzoic acid
-
-
2150-41-6
methyl 2, 4-dimethoxybenzoate
-
-
606-45-1
2-methoxybenzoic acid methyl ester
-
-
5368-81-0
methyl 3-methoxybenzoate
-
-
121-98-2
methyl 4-methoxybenzoate
-
-
2150-38-1
methyl 3,4-dimethoxybenzoate
-
-
1916-07-0
3,4,5-trimethoxybenzoic acid methyl ester
-
-
2150-42-7
methyl 2,3-dimethoxybenzoate
-
-
2150-40-5
methyl 2,5-dimethoxybenzoate
-
-
2150-37-0
methyl 3,5-dimethoxybenzoate
| Conditions | Yield |
|---|---|
|
3,4-Dihydroxybenzoic acid; 4-hydroxysalicylic acid; 3,4,5-trihydroxybenzoic acid; 3,5-Dihydroxybenzoic acid; 2,3-Dihydroxybenzoic acid; 2,5-dihydroxybenzoic acid.; 3-Carboxyphenol; salicylic acid; 4-hydroxy-benzoic acid;
With
sodium hydride;
In
hexane; N,N-dimethyl-formamide;
at 25 ℃;
for 2h;
Inert atmosphere;
Cooling with ice;
methyl iodide;
In
hexane; N,N-dimethyl-formamide;
for 72h;
Inert atmosphere;
|
-
-
186581-53-3,908094-01-9,334-88-3
diazomethane
-
-
C66H68O31
-
-
492-62-6
alpha-D-glucopyranose
-
-
1916-07-0
3,4,5-trimethoxybenzoic acid methyl ester
-
-
4891-62-7,65995-60-0,71307-89-6
dimethyl (S)-4,4',5,5',6,6'-hexamethoxydiphenoate
-
-
82203-13-2,98899-87-7
3-(2,3-Dimethoxy-5-methoxycarbonyl-phenoxy)-4,5,6,4',5',6'-hexamethoxy-biphenyl-2,2'-dicarboxylic acid dimethyl ester
| Conditions | Yield |
|---|---|
|
With
sodium hydroxide;
Yield given. Multistep reaction;
1.) MeOH, reflux, 2.5 h, 2.) ether, 30 min;
|
|
|
With
sodium hydroxide;
Yield given. Multistep reaction. Yields of byproduct given;
1.) MeOH, reflux, 2.5 h, 2.) ether, 30 min;
|
1916-07-0 Upstream products
-
186581-53-3
diazomethane
-
24093-81-0
methyl 3,5-dihydroxy-4-methoxybenzoate
-
118-41-2
Eudesmic acid
-
623-11-0
1-methyl-4-nitrosobenzene
1916-07-0 Downstream products
-
101275-75-6
(piperidine-1-carbonyl)-(3,4,5-trimethoxy-benzoyl)-amine
-
858468-00-5
1,2,3-trimethoxy-5-(prop-1-en-2-yl)benzene
-
267003-32-7
3-(3,4,5-trimethoxyphenyl)-3-pentanol
-
1968-71-4
methyl 2-bromo-3,4,5-trimethoxybenzoate
Relevant Products
-
1-Boc-3-PiperidinoneCAS：98977-36-7
-
6-Chloro-1,3-dimethyl-2,4-(1H,3H)-pyrimidinedioneCAS：6972-27-6
-
(R)-1-Boc-3-AminopiperidineCAS：188111-79-7
