6972-27-6
- Product Name：6-Chloro-1,3-dimethyl-2,4-(1H,3H)-pyrimidinedione
- Molecular Formula：C6H7ClN2O2
- Purity：99%
- Molecular Weight：174.587
Product Details
pd_meltingpoint:109-113 °C
Appearance:white or light white crystal powder
Factory Sells Best Quality 6-Chloro-1,3-dimethyl-2,4-(1H,3H)-pyrimidinedione 6972-27-6 with ISO standards
- Molecular Formula:C6H7ClN2O2
- Molecular Weight:174.587
- Appearance/Colour:white or light white crystal powder
- Vapor Pressure:0.0906mmHg at 25°C
- Melting Point:109-113 °C
- Refractive Index:1.576
- Boiling Point:224.6 °C at 760 mmHg
- PKA:-3.53±0.40(Predicted)
- Flash Point:89.6 °C
- PSA：44.00000
- Density:1.43 g/cm3
- LogP:-0.26260
6-Chloro-1,3-dimethyl-2,4-(1H,3H)-pyrimidinedione(Cas 6972-27-6) Usage
InChI:InChI=1/C6H7ClN2O2/c1-8-4(7)3-5(10)9(2)6(8)11/h3H,1-2H3
6972-27-6 Relevant articles
Doxofylline impurity and preparation method thereof
-
Paragraph 0020-0024, (2019/05/22)
The invention provides a doxofylline imp...
Iodine/persulfate-promoted site-selective direct thiolation of quinolones and uracils
Beukeaw, Danupat,Noikham, Medena,Yotphan, Sirilata
supporting information, (2019/09/03)
A simple and general method for direct t...
Pd/PTABS: Catalyst for Room Temperature Amination of Heteroarenes
Murthy Bandaru, Siva Sankar,Bhilare, Shatrughn,Chrysochos, Nicolas,Gayakhe, Vijay,Trentin, Ivan,Schulzke, Carola,Kapdi, Anant R.
supporting information, p. 473 - 476 (2018/01/28)
A mild and highly efficient catalytic am...
A natural product four methyl uric acid fully synthetic method
-
Paragraph 0033; 0034; 0035, (2017/08/25)
The invention relates to a total synthes...
6972-27-6 Process route
-
-
769-42-6
1,3-dimethylbarbituric acid
-
-
6972-27-6
1,3-Dimethyl-6-chlorouracil
| Conditions | Yield |
|---|---|
|
With
water; trichlorophosphate;
Heating;
|
93% |
|
With
water; trichlorophosphate;
for 6h;
Reflux;
Large scale;
|
92.3% |
|
With
trichlorophosphate;
|
|
|
With
trichlorophosphate;
for 1h;
Yield given;
Heating;
|
|
|
With
trichlorophosphate;
for 2h;
Heating;
|
|
|
With
trichlorophosphate;
|
|
|
With
trichlorophosphate;
In
water;
at 22 - 26 ℃;
Cooling;
Reflux;
|
|
|
With
trichlorophosphate;
In
water;
for 3h;
Cooling;
Reflux;
|
|
|
With
trichlorophosphate;
In
water;
for 3h;
Reflux;
|
|
|
With
trichlorophosphate;
In
water;
for 3h;
Reflux;
Large scale;
|
0.9 kg |
|
With
trichlorophosphate;
In
water;
for 1h;
Inert atmosphere;
Reflux;
|
8 g |
|
With
trichlorophosphate;
In
water;
at 0 - 90 ℃;
for 2.5h;
|
20 g |
-
-
4270-27-3
6-chlorouracil
-
-
6972-27-6
1,3-Dimethyl-6-chlorouracil
| Conditions | Yield |
|---|---|
|
With
sodium hydride;
In
N,N-dimethyl-formamide; mineral oil;
at 70 ℃;
for 3h;
|
6972-27-6 Upstream products
-
6320-15-6
6-chloro-2,4-dimethoxypyrimidine
-
74-88-4
methyl iodide
-
769-42-6
1,3-dimethylbarbituric acid
-
4270-27-3
6-chlorouracil
6972-27-6 Downstream products
-
5770-43-4
6-ethylamino-1,3-dimethyl-1H-pyrimidine-2,4-dione
-
5770-44-5
6-(2-hydroxyethylamino)-1,3-dimethylpyrimidine-2,4(1H,3H)-dion
-
13177-82-7
1,3-dimethyl-6-dimethylaminouracil
-
5770-46-7
6-n-butylamino-1,3-dimethyluracil
Relevant Products
-
-
(R)-(-)-2-MethylpiperazineCAS：75336-86-6
-
3,4,5-Trimethoxybenzoic acid methyl esterCAS：1916-07-0
