51673-83-7
- Product Name：TETRAHYDROPYRAN-2-CARBOXYLIC ACID
- Molecular Formula：C6H10O3
- Purity：99%
- Molecular Weight：130.144
Product Details
China cas 51673-83-7 factory wholesale TETRAHYDROPYRAN-2-CARBOXYLIC ACID at affordable price
- Molecular Formula:C6H10O3
- Molecular Weight:130.144
- Vapor Pressure:0.003mmHg at 25°C
- Refractive Index:1.473
- Boiling Point:264.5 °C at 760 mmHg
- PKA:3.70±0.20(Predicted)
- Flash Point:114.039 °C
- PSA：46.53000
- Density:1.186 g/cm3
- LogP:0.64010
TETRAHYDROPYRAN-2-CARBOXYLIC ACID(Cas 51673-83-7) Usage
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General Description |
Tetrahydropyran-2-carboxylic acid, also known as THP-2-carboxylic acid, is a chemical compound commonly used in organic synthesis and pharmaceutical research. It is a colorless, water-soluble crystalline solid, derived from the natural product (-)-isoleucine. THP-2-carboxylic acid is widely utilized as a chiral building block in the synthesis of pharmaceuticals and other biologically active compounds. This chemical has demonstrated potential therapeutic applications in the treatment of various diseases and has also been used in the development of novel drug delivery systems. It is considered a valuable intermediate in the pharmaceutical industry due to its versatile reactivity and ability to control stereochemistry in organic reactions. |
InChI:InChI=1/C6H10O3/c7-6(8)5-3-1-2-4-9-5/h5H,1-4H2,(H,7,8)
51673-83-7 Relevant articles
Oxidation of partially protected carbohydrates at the nickel hydroxide electrode
Schaefer, Hans J.,Schneider, Roy
, p. 715 - 724 (2007/10/02)
Primary hydroxy groups in pyranoses are ...
51673-83-7 Process route
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100-72-1
Tetrahydropyran-2-methanol
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51673-83-7
tetrahydropyran-2-carboxylic acid
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110-94-1
1,5-pentanedioic acid
| Conditions | Yield |
|---|---|
|
oxidation at the Ni-hydroxide electrode;
|
6% 53% |
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-
51673-83-7
tetrahydropyran-2-carboxylic acid
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(2S,3S,4S,5S)-3-tert-butyl-4-(5-tert-butyl-2-methoxybenzylamino)-5-(2-isopropylphenyl)pyrrolidine-2-carboxylic acid ethyl ester
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(2S,3S,4S,5S)-3-tert-butyl-4-(5-tert-butyl-2-methoxybenzylamino)-5-(2-isopropylphenyl)-1-(tetrahydropyran-2-carbonyl)pyrrolidine-2-carboxylic acid ethyl ester
| Conditions | Yield |
|---|---|
|
tetrahydropyran-2-carboxylic acid;
With
1-chloro-1-(dimethylamino)-2-methyl-1-propene;
In
dichloromethane;
at 0 ℃;
for 0.0833333h;
(2S,3S,4S,5S)-3-tert-butyl-4-(5-tert-butyl-2-methoxybenzylamino)-5-(2-isopropylphenyl)pyrrolidine-2-carboxylic acid ethyl ester;
With
diethylamine;
In
dichloromethane;
at 0 - 20 ℃;
for 1.66667h;
|
100% |
51673-83-7 Upstream products
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100-72-1
Tetrahydropyran-2-methanol
51673-83-7 Downstream products
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147164-53-2
tetrahydropyran-2-carboxylic acid chloride
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84355-44-2
2-carbomethoxytetrahydropyran
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100612-18-8
2-phenyl-1-(tetrahydro-2'H-pyran-2'-yl)-1-ethanone
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73504-72-0
phenyl(tetrahydro-2H-pyran-2-yl)methanone
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