139481-41-7
- Product Name：Ethyl-2-Ethoxy-1-[[(2'-Cyanobiphenyl-4-yl) Methyl] Benzimidazole]-7-Carboxylate
- Molecular Formula：C26H23N3O3
- Purity：99%
- Molecular Weight：425.487
Product Details
Factory Sells Best Quality Ethyl-2-Ethoxy-1-[[(2'-Cyanobiphenyl-4-yl) Methyl] Benzimidazole]-7-Carboxylate 139481-41-7 with stock
- Molecular Formula:C26H23N3O3
- Molecular Weight:425.487
- Boiling Point:637.542 °C at 760 mmHg
- PKA:4.20±0.10(Predicted)
- Flash Point:339.374 °C
- PSA：77.14000
- Density:1.19 g/cm3
- LogP:5.19868
139481-41-7 Relevant articles
Synthesis, characterization of benzimidazole carboxamide derivatives as potent anaplastic lymphoma kinase inhibitor and antioxidant activity
Sam Daniel Prabu,Lakshmanan, Sivalingam,Ramalakshmi,Thirumurugan,Govindaraj, Dharman,Antony, S. Arul
, p. 266 - 278 (2019/01/19)
Novel benzimidazole carboxamide derivati...
1-(CYCLOHEXYLOXYCARBONYLOXY)ETHYL 2-ETHOXY-1-[[2'-(1H-TETRAZOL-5-YL)BIPHENYL-4-YL]METHYL]BENZIMIDAZOLE-7-CARBOXYLATE AND COMPOSITIONS AND METHODS OF PHARMACEUTICAL USE THEREOF
-
, (2008/06/13)
1-(Cyclohexyloxycarbonyloxy)ethyl 2-etho...
139481-41-7 Process route
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78-09-1
orthocarbonic acid tetraethyl ester
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136285-69-3
ethyl 3-amino-2-<<(2'-cyanobiphenyl-4-yl)methyl>amino>benzoate
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![ethyl 1-[(2'-cyano-[1,1']-biphenyl-4-yl)methyl]-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate](/upload/2024/12/97dc1e20-f96f-4d7c-904a-e9c4ed84f552.png)
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139481-41-7
ethyl 1-[(2'-cyano-[1,1']-biphenyl-4-yl)methyl]-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate
| Conditions | Yield |
|---|---|
|
With
acetic acid;
at 80 ℃;
for 1h;
|
-
![ethyl 2-[(2'-cyanobiphenyl-4-yl)methyl]amino-3-nitrobenzoate](/upload/2024/12/55a3c4e8-9269-4f8b-b2b5-0c07438a2cb5.png)
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136285-67-1
ethyl 2-[(2'-cyanobiphenyl-4-yl)methyl]amino-3-nitrobenzoate
-
-
139481-41-7
ethyl 1-[(2'-cyano-[1,1']-biphenyl-4-yl)methyl]-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate
| Conditions | Yield |
|---|---|
|
Multi-step reaction with 2 steps
1: tin(II) chloride dihdyrate / 2 h / 70 °C
2: acetic acid / 1 h / 80 °C
With
tin(II) chloride dihdyrate; acetic acid;
|
139481-41-7 Upstream products
-
136285-67-1
ethyl 2-[(2'-cyanobiphenyl-4-yl)methyl]amino-3-nitrobenzoate
-
78-09-1
orthocarbonic acid tetraethyl ester
-
136285-69-3
ethyl 3-amino-2-<<(2'-cyanobiphenyl-4-yl)methyl>amino>benzoate
-
16533-45-2
ethyl 2-carboxy-3-nitrobenzoate
139481-41-7 Downstream products
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139481-58-6
ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl]benzimidazole-7-carboxylate
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632322-61-3
1-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid
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1397836-41-7
ethyl 2-ethoxy-1-((2′-(N′-hydroxycarbamimidoyl)biphenyl-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate
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139481-33-7
methyl 1-<(2'-cyanobiphenyl-4-yl)methyl>-2,3-dihydro-2-oxo-1H-benzimidazole-7-carboxylate
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