5464-78-8
- Product Name：1-(2-Methoxyphenyl)piperazine hydrochloride
- Molecular Formula：C11H17ClN2O
- Purity：99%
- Molecular Weight：228.722
Product Details
pd_meltingpoint:217-219 °C(lit.)
Appearance:off-white solid
Manufacturer supply high quality 1-(2-Methoxyphenyl)piperazine hydrochloride 5464-78-8 with GMP standards
- Molecular Formula:C11H17ClN2O
- Molecular Weight:228.722
- Appearance/Colour:off-white solid
- Vapor Pressure:5.68E-06mmHg at 25°C
- Melting Point:217-219 °C(lit.)
- Refractive Index:1,574-1,576
- Boiling Point:379.9 °C at 760 mmHg
- Flash Point:154 °C
- PSA：24.50000
- Density:1.057 g/cm3
- LogP:2.30060
1-(2-Methoxyphenyl)piperazine hydrochloride(Cas 5464-78-8) Usage
InChI:InChI=1/C11H16N2O.ClH/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13;/h2-5,12H,6-9H2,1H3;1H
5464-78-8 Relevant articles
Design, synthesis and docking study of 4-arylpiperazine carboxamides as monoamine neurotransmitters reuptake inhibitors
Paudel, Suresh,Sun, Ningning,Khadka, Daulat Bikram,Yoon, Goon,Kim, Kyeong-Man,Cheon, Seung Hoon
, p. 4127 - 4135 (2018/07/21)
Rational drug design method has been use...
Design, synthesis, and systematic evaluation of 4-arylpiperazine- and 4-benzylpiperidine napthyl ethers as inhibitors of monoamine neurotransmitters reuptake
Paudel, Suresh,Min, Xiao,Acharya, Srijan,Khadka, Daulat Bikram,Yoon, Goon,Kim, Kyeong-Man,Cheon, Seung Hoon
, p. 5538 - 5546 (2018/10/09)
Two series of 4-arylpiperazine- and 4-be...
Exploration of substituted arylpiperazine–tetrazoles as promising dual norepinephrine and dopamine reuptake inhibitors
Paudel, Suresh,Acharya, Srijan,Yoon, Goo,Kim, Kyeong-Man,Cheon, Seung Hoon
, p. 5546 - 5555 (2016/10/22)
In the search for potent dual norepineph...
Design, synthesis, and biological evaluation of arylpiperazine-benzylpiperidines with dual serotonin and norepinephrine reuptake inhibitory activities
Paudel, Suresh,Acharya, Srijan,Kim, Kyeong-Man,Cheon, Seung Hoon
, p. 2137 - 2145 (2016/04/20)
The limitations of established serotonin...
5464-78-8 Process route
-
-
95520-98-2
tert-butyl 4-(2-methoxyphenyl)piperazine-1-carboxylate
-
-
5464-78-8
1-(2-methoxyphenyl)piperazine hydrochloride
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
diethyl ether;
|
90.08% |
|
With
hydrogenchloride;
In
diethyl ether;
for 2h;
|
90.08% |
|
With
hydrogenchloride;
In
ethyl acetate;
at 20 ℃;
for 1.5h;
|
-
-
821-48-7
bis-(2-chloroethyl)amine hydrochloride
-
-
90-04-0
2-methoxy-phenylamine
-
-
5464-78-8
1-(2-methoxyphenyl)piperazine hydrochloride
| Conditions | Yield |
|---|---|
|
With
2-(2-methoxyethoxy)ethyl alcohol;
at 150 ℃;
for 12h;
|
74% |
|
With
2-(2-methoxyethoxy)ethyl alcohol;
at 150 ℃;
for 12h;
|
74% |
|
In
diethylene glycol dimethyl ether;
at 150 ℃;
|
74% |
|
at 150 ℃;
|
5464-78-8 Upstream products
-
95520-98-2
tert-butyl 4-(2-methoxyphenyl)piperazine-1-carboxylate
-
578-57-4
2-bromoanisole
-
821-48-7
bis-(2-chloroethyl)amine hydrochloride
-
90-04-0
2-methoxy-phenylamine
5464-78-8 Downstream products
-
62811-34-1
1-(8,9-dihydro-7H-benzocyclohepten-6-ylmethyl)-4-(2-methoxy-phenyl)-piperazine
-
95395-50-9
1-crotonoyl-4-(2-methoxyphenyl)piperazine
-
135561-98-7
4-(3,5-Dimethyl-pyrazol-1-yl)-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-5H-pyridazino[4,5-b]indole
-
110164-58-4
N-(2-carbomethoxythien-3-yl)-N'-[2-[4-[2-methoxyphenyl)piperazin-1-yl)ethyl]urea
Relevant Products
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-
PTAA (Poly[bis(4-phenyl)(2,5,6-trimethylphenyl)amineCAS：1333317-99-9
-
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