85064-61-5
- Product Name：2-(tetrahydro-2H-pyran-4-yl)acetic acid
- Molecular Formula：C7H12O3
- Purity：99%
- Molecular Weight：144.17
Product Details
pd_meltingpoint:48-50 °C
Appearance:white to light yellow crystal powder
Excellent chemical plant bulk supply 2-(tetrahydro-2H-pyran-4-yl)acetic acid 85064-61-5
- Molecular Formula:C7H12O3
- Molecular Weight:144.17
- Appearance/Colour:white to light yellow crystal powder
- Vapor Pressure:0.000738mmHg at 25°C
- Melting Point:48-50 °C
- Boiling Point:285.1 °C at 760 mmHg
- PKA:4.60±0.10(Predicted)
- Flash Point:119.2 °C
- PSA：46.53000
- Density:1.111 g/cm3
- LogP:0.88770
Tetrahydropyranyl-4-acetic acid(Cas 85064-61-5) Usage
InChI:InChI=1/C7H12O3/c8-7(9)5-6-1-3-10-4-2-6/h6H,1-5H2,(H,8,9)/p-1
85064-61-5 Relevant articles
COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS
-
, (2015/02/02)
The present disclosure is generally dire...
Hepatitis C Virus Inhibitors
-
, (2015/02/25)
The present disclosure is generally dire...
Synthesis and activity of putative small-molecule inhibitors of the F-box protein SKP2
Shouksmith, Andrew E.,Evans, Laura E.,Tweddle, Deborah A.,Miller, Duncan C.,Willmore, Elaine,Newell, David R.,Golding, Bernard T.,Griffin, Roger J.
, p. 660 - 679 (2015/04/27)
The tetrahydropyran 4-(((3-(2,2-dimethyl...
NDM INHIBITOR
-
Paragraph 0114; 0117-0118, (2014/06/24)
An objective of the present invention is...
85064-61-5 Process route
-
-
103260-44-2
ethyl tetrahydropyran-4-acetate
-
-
85064-61-5
2-(tetrahydro-2H-pyran-4-yl)acetic acid
| Conditions | Yield |
|---|---|
|
With
water; sodium hydroxide;
In
methanol;
at 0 - 20 ℃;
for 15h;
|
94% |
|
With
sodium hydroxide;
In
ethanol;
for 4h;
|
1.1 g |
|
With
sodium hydroxide;
In
methanol; water;
|
|
|
With
potassium hydroxide;
In
ethanol;
for 18h;
|
-
-
156002-64-1
methyl 2-(tetrahydro-2H-pyran-4-yl)acetate
-
-
85064-61-5
2-(tetrahydro-2H-pyran-4-yl)acetic acid
| Conditions | Yield |
|---|---|
|
With
lithium hydroxide monohydrate;
In
tetrahydrofuran; water;
at 60 ℃;
for 1.5h;
Inert atmosphere;
|
95% |
|
With
sodium hydroxide;
In
methanol; water;
at 20 ℃;
|
|
|
methyl 2-(tetrahydro-2H-pyran-4-yl)acetate;
With
sodium hydroxide; water;
at 20 ℃;
With
hydrogenchloride;
In
water;
pH=2;
|
85064-61-5 Upstream products
-
850429-50-4
2-(tetrahydro-2H-pyran-4-yl)acetonitrile
-
14390-06-8
tetrahydropyran-4-yl-malonic acid
-
103260-44-2
ethyl tetrahydropyran-4-acetate
-
29943-42-8
Tetrahydro-4H-pyran-4-one
85064-61-5 Downstream products
-
130290-79-8
4-tetrahydropyranmethylamine
-
40500-05-8
2-(tetrahydro-2H-pyran-4-yl)acetyl chloride
-
929556-48-9
benzyl 2-(tetrahydro-2H-pyran-4-yl)acetate
-
815618-35-0
(R)-4-benzyl-3-(2-(tetrahydro-2H-pyran-4-yl)acetyl)oxazolidin-2-one
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