
157688-46-5
- Product Name:N-Boc-4-piperidineacetic acid
- Molecular Formula:C12H21NO4
- Purity:99%
- Molecular Weight:243.303
Product Details
pd_meltingpoint:96-98 °C
Appearance:off-white solid
Manufacturer supply N-Boc-4-piperidineacetic acid 157688-46-5 with sufficient stock and high standard
- Molecular Formula:C12H21NO4
- Molecular Weight:243.303
- Appearance/Colour:off-white solid
- Vapor Pressure:1.37E-06mmHg at 25°C
- Melting Point:96-98 °C
- Boiling Point:373 °C at 760 mmHg
- PKA:4.66±0.10(Predicted)
- Flash Point:179.4 °C
- PSA:66.84000
- Density:1.121 g/cm3
- LogP:2.04610
1-Boc-4-piperidylacetic acid(Cas 157688-46-5) Usage
InChI:InChI=1/C12H21NO4/c1-12(2,3)17-11(16)13-6-4-9(5-7-13)8-10(14)15/h9H,4-8H2,1-3H3,(H,14,15)/p-1
157688-46-5 Relevant articles
GLP-1R AGONISTS AND USES THEREOF
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Page/Page column 64; 201, (2020/06/10)
Provided are compounds of Formula (I) an...
NITROGENOUS HETEROCYCLIC AMIDE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL APPLICATION
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Paragraph 0170, (2018/12/07)
Provided are a compound represented by f...
High-efficiency synthesis method of methyl 4-piperidineacetate
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Paragraph 0034; 0044; 0046; 0054; 0064; 0074, (2019/01/14)
The invention discloses a high-efficienc...
Synthesis, biological evaluation, X-ray molecular structure and molecular docking studies of RGD mimetics containing 6-amino-2,3-dihydroisoindolin-1-one fragment as ligands of integrin αiIbβ3
Krysko, Andrei A.,Samoylenko, Georgiy V.,Polishchuk, Pavel G.,Fonari, Marina S.,Kravtsov, Victor Ch.,Andronati, Sergei A.,Kabanova, Tatyana A.,Lipkowski, Janusz,Khristova, Tetiana M.,Kuz'Min, Victor E.,Kabanov, Vladimir M.,Krysko, Olga L.,Varnek, Alexandre A.
, p. 4646 - 4661 (2013/07/26)
A series of novel RGD mimetics containin...
157688-46-5 Process route
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59184-90-6
ethyl (piperidin-4-yl)acetate

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24424-99-5
di-tert-butyl dicarbonate

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161949-04-8
4-[3-(2-Piperidin-4-ylacetyl)carbazoyl]-2-(carboxymethoxy)phenoxyacetic acid, trifluoroacetic acid salt

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157688-46-5
2-(1-(tert-butoxycarbonyl)piperidin-4-yl)acetic acid
Conditions | Yield |
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In
methanol; sodium hydroxide; dichloromethane;
|
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59184-90-6
ethyl (piperidin-4-yl)acetate

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157688-46-5
2-(1-(tert-butoxycarbonyl)piperidin-4-yl)acetic acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps
1: tetrahydrofuran / 4 h / 55 °C / Inert atmosphere
2: water; sodium hydroxide / ethanol / 1 h / 90 °C
With
water; sodium hydroxide;
In
tetrahydrofuran; ethanol;
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157688-46-5 Upstream products
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tert-butyldicarbonate
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4-piperidinylacetic acid
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di-tert-butyl dicarbonate
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2-(piperidin-4-yl)acetic acid hydrochloride
157688-46-5 Downstream products
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4-(2-hydroxyethyl)piperidine-1-carboxylic acid tert-butyl ester
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tert-butyl 4-{2-[methoxy(methyl)amino]-2-oxoethyl}piperidine-1-carboxylate
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1-t-Butoxycarbonyl-4-(methoxycarbonylmethyl)piperidine
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1-Boc-4-Cyanopiperidine
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