259809-47-7
- Product Name：6-TERT-BUTYL 2-METHYL 7,8-DIHYDRO-1,6-NAPHTHYRIDINE-2,6(5H)-DICARBOXYLATE
- Molecular Formula：C15H20 N2 O4
- Purity：99%
- Molecular Weight：292.335
Product Details
Factory Sells Best Quality 6-TERT-BUTYL 2-METHYL 7,8-DIHYDRO-1,6-NAPHTHYRIDINE-2,6(5H)-DICARBOXYLATE 259809-47-7 with GMP standards
- Molecular Formula:C15H20N2O4
- Molecular Weight:292.335
- Vapor Pressure:0mmHg at 25°C
- Refractive Index:1.537
- Boiling Point:432.899°C at 760 mmHg
- PKA:1.52±0.20(Predicted)
- Flash Point:215.61°C
- PSA：68.73000
- Density:1.19g/cm3
- LogP:2.09930
6-TERT-BUTYL 2-METHYL 7,8-DIHYDRO-1,6-NAPHTHYRIDINE-2,6(5H)-DICARBOXYLATE(Cas 259809-47-7) Usage
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General Description |
6-TERT-BUTYL 2-METHYL 7,8-DIHYDRO-1,6-NAPHTHYRIDINE-2,6(5H)-DICARBOXYLATE is a chemical compound that belongs to the class of naphthyridine carboxylates. It is a derivative of 1,6-naphthyridine and contains a tert-butyl group and a methyl group. It is commonly used in medicinal and pharmaceutical research as a building block for the synthesis of potential drug candidates. 6-TERT-BUTYL 2-METHYL 7,8-DIHYDRO-1,6-NAPHTHYRIDINE-2,6(5H)-DICARBOXYLATE has shown potential in the treatment of various diseases and conditions, and its unique chemical structure makes it valuable for drug discovery and development. Its properties are being further explored for potential therapeutic applications. |
InChI:InChI=1/C15H20N2O4/c1-15(2,3)21-14(19)17-8-7-11-10(9-17)5-6-12(16-11)13(18)20-4/h5-6H,7-9H2,1-4H3
259809-47-7 Relevant articles
PIPERIDINYL AMINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE
-
Page/Page column 56-57, (2021/04/03)
The present invention relates to compoun...
SUBSTITUTE 1, 6-NAPHTHYRIDINES FOR USE AS SCD INHIBITORS
-
Page/Page column 42, (2009/06/27)
The present invention relates to substit...
Synthesis and conformational analysis of a non-amidine factor Xa inhibitor that incorporates 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine as S4 binding element
Haginoya, Noriyasu,Kobayashi, Syozo,Komoriya, Satoshi,Yoshino, Toshiharu,Suzuki, Makoto,Shimada, Takashi,Watanabe, Kengo,Hirokawa, Yumiko,Furugori, Taketoshi,Nagahara, Takayasu
, p. 5167 - 5182 (2007/10/03)
Our exploratory study was based on the c...
259809-47-7 Process route
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24424-99-5
di-tert-butyl dicarbonate
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-
259809-46-6
6-(tert-butoxycarbonyl)-2-cyano-5,6,7,8-tetrahydro-1,6-naphthyridine
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-
259809-47-7
6-(tert-butoxycarbonyl)-2-methoxycarbonyl-5,6,7,8-tetrahydro-1,6-naphthyridine
| Conditions | Yield |
|---|---|
|
6-(tert-butoxycarbonyl)-2-cyano-5,6,7,8-tetrahydro-1,6-naphthyridine;
With
hydrogenchloride;
In
methanol; water;
at 100 ℃;
for 3h;
With
sodium hydrogencarbonate;
In
tetrahydrofuran; methanol; water;
di-tert-butyl dicarbonate;
In
tetrahydrofuran; methanol; water;
at 20 ℃;
for 0.5h;
|
55% |
-
-
67-56-1
methanol
-
-
201230-82-2
carbon monoxide
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![2-chloro-7,8-dihydro-5H-[1,6]naphthyridine-6-carboxylic acid tert-butyl ester](/upload/2024/12/04434bed-0805-4dfb-a294-c12444e092b1.png)
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1151665-15-4
2-chloro-7,8-dihydro-5H-[1,6]naphthyridine-6-carboxylic acid tert-butyl ester
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-
259809-47-7
6-(tert-butoxycarbonyl)-2-methoxycarbonyl-5,6,7,8-tetrahydro-1,6-naphthyridine
| Conditions | Yield |
|---|---|
|
With
1,3-bis-(diphenylphosphino)propane; palladium diacetate; triethylamine;
at 100 ℃;
for 16h;
|
930 mg |
259809-47-7 Upstream products
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24424-99-5
di-tert-butyl dicarbonate
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1057855-79-4
5,6,7,8-tetrahydro-[1,6]naphthyridine-2-carboxylic acid methyl ester
-
3612-20-2
1-phenylmethyl-4-piperidone
-
80957-68-2
5,6,7,8-tetrahydro-1,6-naphthyridine
259809-47-7 Downstream products
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259809-49-9
6-(tert-butoxycarbonyl)-5,6,7,8-tetrahydro-1,6-naphthyridine-2-carboxylic acid
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1868106-31-3
tert-butyl 2-(hydroxymethyl)-7,8-dihydro-5H-1,6-naphthyridine-6-carboxylate
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